Euro
USD
British Pound
NULL
Product Description
5-Nitroso-8-quinolinol is a quinoline inhibitor of histone deacetylase (HDAC). It inhibits HDAC activity in vitro and causes reactive oxygen species, DNA damage and apoptosis in MCF-7 breast cancer cells at a concentration of 10 μM. It exhibits anticancer activity in mice. It inhibits growth of Toxoplasma gondii with an EC₅₀ of 80 nM.
5-Nitroso-8-quinolinol is a quinoline inhibitor of histone deacetylase (HDAC). It inhibits HDAC activity in vitro and causes reactive oxygen species, DNA damage and apoptosis in MCF-7 breast cancer cells at a concentration of 10 μM. It exhibits anticancer activity in mice. It inhibits growth of Toxoplasma gondii with an EC₅₀ of 80 nM.
Biovision | B2825 | 5-Nitroso-8-quinolinol DataSheet
Alternate Name/Synonyms: 5-Nitroso-8-hydroxyquinoline, 5-Nitrosoquinolin-8-ol, 5-Nitroso-8-cinnolinol, 5-Nitrosooxine, 8-Hydroxy-5-nitrosoquinoline, (5Z)-5-hydroxyimino-quinolin-8-one, (5Z)-5,8-quinolinedione 5-oxime, NSC 3852
Appearance: Crystalline solid
Formulation:
CAS Number: 3565-26-2
Structure Available?: True
Peptide sequence:
Salt Form: False
Molecular Formula: C₉H₆N₂O₂
Molecular Weight: 174.16
Cell-Permeable?: True
Purity: ≥95%
Solubilities: ~1 mg/ml in DMF in 0, ~2 mg/ml in in DMSO
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: An inhibitor of HDAC
MDL Number: MFCD00041862
PubChem CID: 19103
SMILES: C1=CC2=C(C=CC(=C2N=C1)O)N=O
InChi: InChI=1S/C9H6N2O2/c12-8-4-3-7(11-13)6-2-1-5-10-9(6)8/h1-5,12H
InChi Key: RZWRYPGAUIOOMK-UHFFFAOYSA-N
