Product Description
AFN-1252 is a potent inhibitor of enoyl-acyl carrier protein reductase (FabI). Inhibits all clinical isolates of Staphylococcus aureus (n = 502) and Staphylococcus epidermidis (n = 51) tested, including methicillin (meticillin)-resistant isolates, at concentrations of AFN-1252 is a potent inhibitor of enoyl-acyl carrier protein reductase (FabI). Inhibits all clinical isolates of Staphylococcus aureus (n = 502) and Staphylococcus epidermidis (n = 51) tested, including methicillin (meticillin)-resistant isolates, at concentrations of Biovision | B3338 | AFN-1252 DataSheet Alternate Name/Synonyms: AFN1252
(E)-N-methyl-N-((3-methylbenzofuran-2-yl)methyl)-3-(7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl)acrylamide
AFN12520000 Appearance: White to off-white solid Formulation: CAS Number: 620175-39-5 Structure Available?: Yes Peptide sequence: N/A Salt Form: No Molecular Formula: C₂₂H₂₁N₃O₃ Molecular Weight: 375.43 Cell-Permeable?: TRUE Purity: ≥98% Solubilities: 5 mg/ml DMSO Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure. Country of Origin: USA Tag Line: A potent inhibitor of enoyl-acyl carrier protein reductase (FabI) MDL Number: PubChem CID: 10407120 SMILES: O=C(N(C)CC1=C(C)C2=CC=CC=C2O1)/C=C/C3=CC(CC4)=C(N=C3)NC4=O InChi: InChI=1S/C22H21N3O3/c1-14-17-5-3-4-6-18(17)28-19(14)13-25(2)21(27)10-7-15-11-16-8-9-20(26)24-22(16)23-12-15/h3-7,10-12H,8-9,13H2,1-2H3,(H,23,24,26)/b10-7+ InChi Key: QXTWSUQCXCWEHF-JXMROGBWSA-N