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Product Description
AM-679 is a potent 5-lipoxygenase-activating protein (FLAP) inhibitor with IC₅₀s of 2.2 nM/0.6 nM/154 nM for FLAP binding/hLA/hWB respectively.
AM-679 is a potent 5-lipoxygenase-activating protein (FLAP) inhibitor with IC₅₀s of 2.2 nM/0.6 nM/154 nM for FLAP binding/hLA/hWB respectively.
Biovision | B2521 | AM-679 DataSheet
Alternate Name/Synonyms: AM679 3-[5-[[(2S)-1-acetyl-2,3-dihydroindol-2-yl]methoxy]-3-tert-butylsulfanyl-1-[[4-(5-methoxypyrimidin-2-yl)phenyl]methyl]indol-2-yl]-2,2-dimethylpropanoic acid
Appearance: Crystalline solid
Formulation:
CAS Number: 1206880-66-1
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₄₀H₄₄N₄O₅S
Molecular Weight: 692.9
Cell-Permeable?: True
Purity: ≥98%
Solubilities: >50 mg/ml in DMSO
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: A potent 5-lipoxygenase-activating protein (FLAP) inhibitor
MDL Number:
PubChem CID: 44627267
SMILES: CC(=O)N1C(CC2=CC=CC=C21)COC3=CC4=C(C=C3)N(C(=C4SC(C)(C)C)CC(C)(C)C(=O)O)CC5=CC=C(C=C5)C6=NC=C(C=N6)OC
InChi: InChI=1S/C40H44N4O5S/c1-25(45)44-29(18-28-10-8-9-11-33(28)44)24-49-30-16-17-34-32(19-30)36(50-39(2,3)4)35(20-40(5,6)38(46)47)43(34)23-26-12-14-27(15-13-26)37-41-21-31(48-7)22-42-37/h8-17,19,21-22,29H,18,20,23-24H2,1-7H3,(H,46,47)/t29-/m0/s1
InChi Key: VYXWHVDEWWHDLH-LJAQVGFWSA-N
