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Product Description
BC-1618 is a potent Fbxo48 inhibitory compound that stimulates Ampk-dependent signaling (via preventing activated pAmpkα from Fbxo48-mediated degradation). Fbxo48 and was much more potent than metformin in increasing Ampk function. BC1618 promotes mitochondrial fission, facilitates autophagy and improves hepatic insulin sensitivity.
BC-1618 is a potent Fbxo48 inhibitory compound that stimulates Ampk-dependent signaling (via preventing activated pAmpkα from Fbxo48-mediated degradation). Fbxo48 and was much more potent than metformin in increasing Ampk function. BC1618 promotes mitochondrial fission, facilitates autophagy and improves hepatic insulin sensitivity.
Biovision | B3333 | BC-1618 DataSheet
Alternate Name/Synonyms: BC1618 2-Propanol, 1-[bis(phenylmethyl)amino]-3-[4-(trifluoromethyl)phenoxy]-
Appearance: Solid
Formulation:
CAS Number: 2222094-18-8
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₄H₂₄F₃NO₂
Molecular Weight: 415.45
Cell-Permeable?: TRUE
Purity: ≥98%
Solubilities: >50 mg/ml DMSO
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: An orally active Fbxo48 inhibitor
MDL Number:
PubChem CID:
SMILES: OC(COC1=CC=C(C(F)(F)F)C=C1)CN(CC2=CC=CC=C2)CC3=CC=CC=C3
InChi: InChI=1S/C24H24F3NO2/c25-24(26,27)21-11-13-23(14-12-21)30-18-22(29)17-28(15-19-7-3-1-4-8-19)16-20-9-5-2-6-10-20/h1-14,22,29H,15-18H2
InChi Key: LGTYABNNHILKHF-UHFFFAOYSA-N
