Euro
USD
British Pound
NULL
Product Description
cFMS Receptor Inhibitor IV is a furan carboxamide compound that is a potent, reversible, and ATP-competitive inhibitor of cFMS (Colony-stimulating Factor-1 Receptor) Tyrosine Kinase. It blocks cFMS autophosphorylation in CSF-1/M-CSF-stimulated HEK-293 cells and in cell-free in vitro kinase assays with IC₅₀ values of 76 nM and 17 nM respectively.
cFMS Receptor Inhibitor IV is a furan carboxamide compound that is a potent, reversible, and ATP-competitive inhibitor of cFMS (Colony-stimulating Factor-1 Receptor) Tyrosine Kinase. It blocks cFMS autophosphorylation in CSF-1/M-CSF-stimulated HEK-293 cells and in cell-free in vitro kinase assays with IC₅₀ values of 76 nM and 17 nM respectively.
Biovision | B2922 | cFMS Receptor Inhibitor IV DataSheet
Alternate Name/Synonyms: cFMS Receptor Tyrosine Kinase Inhibitor; 5-cyano-N-(2,5-di(piperidin-1-yl)phenyl)furan-2-carboxamide; CSF-1 Receptor Inhibitor IV
Appearance: Solid
Formulation:
CAS Number: 959626-45-0
Structure Available?: True
Peptide sequence:
Salt Form: false
Molecular Formula: C₂₂H₂₆N₄O₂
Molecular Weight: 378.47
Cell-Permeable?: True
Purity: 97%
Solubilities: 5 mg/ml in in DMSO
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: An inhibitor of cFMS/CSF-1R
MDL Number:
PubChem CID: 28408236
SMILES: C1CCN(CC1)C2=CC(=C(C=C2)N3CCCCC3)NC(=O)C4=CC=C(O4)C#N
InChi: InChI=1S/C22H26N4O2/c23-16-18-8-10-21(28-18)22(27)24-19-15-17(25-11-3-1-4-12-25)7-9-20(19)26-13-5-2-6-14-26/h7-10,15H,1-6,11-14H2,(H,24,27)
InChi Key: FQGXFVDABCBEFW-UHFFFAOYSA-N
