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Product Description
Fluvoxamine is an inhibitor of 5-hydroxytryptamine (5-HT) re-uptake. It inhibits the uptake of 5-hydroxytryptamine in guinea-pig blood platelets with a pI₅₀ (the negative logarithm of the molar concentration causing 50 % inhibition) of 6.4. It also has a high affinity at the sigma-1 receptor. It is used as an antidepressant and preliminary studies have shown that fluvoxamine is beneficial in reducing clinical deterioration in COVID-19.
Fluvoxamine is an inhibitor of 5-hydroxytryptamine (5-HT) re-uptake. It inhibits the uptake of 5-hydroxytryptamine in guinea-pig blood platelets with a pI₅₀ (the negative logarithm of the molar concentration causing 50 % inhibition) of 6.4. It also has a high affinity at the sigma-1 receptor. It is used as an antidepressant and preliminary studies have shown that fluvoxamine is beneficial in reducing clinical deterioration in COVID-19.
Biovision | B3118 | Fluvoxamine Maleate DataSheet
Alternate Name/Synonyms: (Z)-but-2-enedioic acid;2-[(E)-[5-methoxy-1-[4-(trifluoromethyl)phenyl]pentylidene]amino]oxyethanamine; 5-Methoxy-4'-trifluoromethylvalerophenone (E)-O-2-aminoethyloxime monomaleate; (E)-5-Methoxy-1-[4-(trifluoromethyl)phenyl]-1-pentanone O-(2-Aminoethyl)oxime Maleate
Appearance: White powder
Formulation:
CAS Number: 61718-82-9
Structure Available?: TRUE
Peptide sequence:
Salt Form: TRUE
Molecular Formula: C₁₉H₂₅F₃N₂O₆
Molecular Weight: 434.4
Cell-Permeable?: True
Purity: ≥ 98% (HPLC)
Solubilities: ~5 mg/ml in PBS (pH 7.2) ~25 mg/ml in Ethanol ~30 mg/ml in DMSO and DMF
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: An inhibitor of 5-hydroxytryptamine (5-HT) re-uptake
MDL Number: MFCD00269809
PubChem CID: 9560989
SMILES: COCCCCC(=NOCCN)C1=CC=C(C=C1)C(F)(F)F.C(=CC(=O)O)C(=O)O
InChi: InChI=1S/C15H21F3N2O2.C4H4O4/c1-21-10-3-2-4-14(20-22-11-9-19)12-5-7-13(8-6-12)15(16,17)18;5-3(6)1-2-4(7)8/h5-8H,2-4,9-11,19H2,1H3;1-2H,(H,5,6)(H,7,8)/b20-14+;2-1-
InChi Key: LFMYNZPAVPMEGP-PIDGMYBPSA-N
