Euro
USD
British Pound
NULL
Product Description
Gabexate is an inhibitor of serine proteases. It inhibits plasma kallikrein, thrombin, plasmin, factor Xa with Ki values of 0.2 μM, 0.97 μM, 1.6 μM and 8.5 μM. It exerts an anticoagulant effect on the clotting activity of thrombin. It inhibits LPS-induced TNF-alpha production in monocytes by inhibiting activation of both NF-kappaB and activator protein-1. It slightly inhibits SARS-CoV-2 S-driven host cell entry in lung cells.
Gabexate is an inhibitor of serine proteases. It inhibits plasma kallikrein, thrombin, plasmin, factor Xa with Ki values of 0.2 μM, 0.97 μM, 1.6 μM and 8.5 μM. It exerts an anticoagulant effect on the clotting activity of thrombin. It inhibits LPS-induced TNF-alpha production in monocytes by inhibiting activation of both NF-kappaB and activator protein-1. It slightly inhibits SARS-CoV-2 S-driven host cell entry in lung cells.
Biovision | B3058 | Gabexate mesylate DataSheet
Alternate Name/Synonyms: FOY; Megacart; ethyl 4-[6-(diaminomethylideneamino)hexanoyloxy]benzoate;methanesulfonic acid; 4-[[6-[(aminoiminomethyl)amino]-1-oxohexyl]oxy]benzoic acid ethyl ester mesylate; [Ethyl p-(6-guanidinohexanoyloxy) benzoate]methanesulfonate
Appearance: White solid
Formulation:
CAS Number: 56974-61-9
Structure Available?: TRUE
Peptide sequence:
Salt Form: TRUE
Molecular Formula: C₁₇H₂₇N₃O₇S
Molecular Weight: 417.48
Cell-Permeable?: TRUE
Purity: ≥97%
Solubilities: ~25 mg/ml in DMSO and DMF
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: An inhibitor of serine proteases
MDL Number: MFCD00210299
PubChem CID: 6604561
SMILES: CCOC(=O)C1=CC=C(C=C1)OC(=O)CCCCCN=C(N)N.CS(=O)(=O)O
InChi: InChI=1S/C16H23N3O4.CH4O3S/c1-2-22-15(21)12-7-9-13(10-8-12)23-14(20)6-4-3-5-11-19-16(17)18;1-5(2,3)4/h7-10H,2-6,11H2,1H3,(H4,17,18,19);1H3,(H,2,3,4)
InChi Key: DNTNDFLIKUKKOC-UHFFFAOYSA-N
