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Product Description
GSA 10 is a novel, potent activator of the smoothened receptor (Smo). GSA 10 acts at Smo and promotes the differentiation of multipotent mesenchymal progenitor cells into osteoblasts (EC₅₀ = 1.2 µM). GSA 10 does not recognize the classic bodipy-cyclopamine binding site like other Smo agonists.
GSA 10 is a novel, potent activator of the smoothened receptor (Smo). GSA 10 acts at Smo and promotes the differentiation of multipotent mesenchymal progenitor cells into osteoblasts (EC₅₀ = 1.2 µM). GSA 10 does not recognize the classic bodipy-cyclopamine binding site like other Smo agonists.
Biovision | B3065 | GSA 10 DataSheet
Alternate Name/Synonyms: Propyl 4-(1-hexyl-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxamido)benzoate; propyl 4-[(1-hexyl-4-hydroxy-2-oxoquinoline-3-carbonyl)amino]benzoate; 4-[(1-Hexyl-4-hydroxy-2-oxo-1,2-dihydro-quinoline-3-carbonyl)-amino]-benzoic acid propyl ester
Appearance: White to light brown solid
Formulation:
CAS Number: 300833-95-8
Structure Available?: TRUE
Peptide sequence:
Salt Form: FALSE
Molecular Formula: C₂₆H₃₀N₂O₅
Molecular Weight: 450.53
Cell-Permeable?: TRUE
Purity: ≥95%
Solubilities: ~1 mg/ml in DMSO
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: An activator of the smoothened receptor
MDL Number: MFCD01128015
PubChem CID: 54683103
SMILES: CCCCCCN1C2=CC=CC=C2C(=C(C1=O)C(=O)NC3=CC=C(C=C3)C(=O)OCCC)O
InChi: InChI=1S/C26H30N2O5/c1-3-5-6-9-16-28-21-11-8-7-10-20(21)23(29)22(25(28)31)24(30)27-19-14-12-18(13-15-19)26(32)33-17-4-2/h7-8,10-15,29H,3-6,9,16-17H2,1-2H3,(H,27,30)
InChi Key: MDLUYYGRCGDKGL-UHFFFAOYSA-N
