Euro
USD
British Pound
NULL
Product Description
GSK3484862 (GSKMI-714) is a selective, reversible, non-covalent DNMT1 (DNA Methyltransferase 1) inhibitor. Potently inhibits the methyltransferase activity of DNMT1, but not DNMT family members DNMT3A or DNMT3B.
GSK3484862 (GSKMI-714) is a selective, reversible, non-covalent DNMT1 (DNA Methyltransferase 1) inhibitor. Potently inhibits the methyltransferase activity of DNMT1, but not DNMT family members DNMT3A or DNMT3B.
Biovision | B3326 | GSK-3484862 DataSheet
Alternate Name/Synonyms: (2R)-2-[3,5-dicyano-6-(dimethylamino)-4-ethylpyridin-2-yl]sulfanyl-2-phenylacetamide GSKMI-714
Appearance: Solid
Formulation:
CAS Number: 2170136-65-7
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₉H₁₉N₅OS
Molecular Weight: 365.45
Cell-Permeable?: TRUE
Purity: ≥98%
Solubilities: >20 mg/ml DMSO
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: A non-covalent Dnmt1 inhibitor
MDL Number:
PubChem CID: 132233666
SMILES: CCC1=C(C(=NC(=C1C#N)SC(C2=CC=CC=C2)C(=O)N)N(C)C)C#N
InChi: InChI=1S/C19H19N5OS/c1-4-13-14(10-20)18(24(2)3)23-19(15(13)11-21)26-16(17(22)25)12-8-6-5-7-9-12/h5-9,16H,4H2,1-3H3,(H2,22,25)/t16-/m1/s1
InChi Key: KIEQQZZDWUNUQK-MRXNPFEDSA-N
