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Product Description
(−)-Huperzine A is a potent and reversible inhibitor of acetylcholinesterase. It shows an IC₅₀ value of 82 nM against acetylcholinesterase in the rat cortex in vitro. It also acts as an antagonist of the N-methyl-D-aspartate (NMDA) receptor and inhibits NMDA induced toxicity. It is beneficial in improving cognitive function in Alzheimer’s disease.
(−)-Huperzine A is a potent and reversible inhibitor of acetylcholinesterase. It shows an IC₅₀ value of 82 nM against acetylcholinesterase in the rat cortex in vitro. It also acts as an antagonist of the N-methyl-D-aspartate (NMDA) receptor and inhibits NMDA induced toxicity. It is beneficial in improving cognitive function in Alzheimer’s disease.
Biovision | B3095 | (−)-Huperzine A DataSheet
Alternate Name/Synonyms: Selagine, (1R,9R)-1-amino-13-ethylidene-11-methyl-6-azatricyclo[7.3.1.02,7]trideca-2(7),3,10-trien-5-one; 5,9-Methanocycloocta[b]pyridin-2(1H)-one, 5-amino-11-ethylidene-5,6,9,10-tetrahydro-7-methyl-, (5R,9R,11E)-
Appearance: White crystalline powder
Formulation:
CAS Number: 102518-79-6
Structure Available?: TRUE
Peptide sequence:
Salt Form: FALSE
Molecular Formula: C₁₅H₁₈N₂O
Molecular Weight: 242.32
Cell-Permeable?: True
Purity: ≥ 98%
Solubilities: ~20 mg/ml in DMSO
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: A potent and reversible inhibitor of acetylcholinesterase
MDL Number: MFCD01714949
PubChem CID: 449069
SMILES: CC=C1C2CC3=C(C1(CC(=C2)C)N)C=CC(=O)N3
InChi: InChI=1S/C15H18N2O/c1-3-11-10-6-9(2)8-15(11,16)12-4-5-14(18)17-13(12)7-10/h3-6,10H,7-8,16H2,1-2H3,(H,17,18)/t10-,15+/m0/s1
InChi Key: ZRJBHWIHUMBLCN-ZUZCIYMTSA-N
