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Product Description
ING-2 is a yellow-green fluorescent intracellular sodium Na⁺ indicator. It is a small, synthetic fluorochrome fused with a Na⁺-binding moiety. When Na⁺ binds to ING-2, the quenching is relieved, and the fluorescence dramatically increases. The spectral properties (Ex/Em: 525 nm/545 nm) and large dynamic range make ING-2 the best Na⁺ indicator for high-throughput screening applications targeting Na⁺ channels, and non-selective monovalent cation channels. ING-2 has a more physiologically relevant affinity (Kd = 20 mM) than ING-1 (Kd = 92 mM). ING-2 TMA+ Salt is the water soluble, membrane impermeable form of the sodium indicator. It can be used in lipid membrane-free systems, in liposomes or can be introduced into cells by electroporation, microinjection or other methods.
ING-2 is a yellow-green fluorescent intracellular sodium Na⁺ indicator. It is a small, synthetic fluorochrome fused with a Na⁺-binding moiety. When Na⁺ binds to ING-2, the quenching is relieved, and the fluorescence dramatically increases. The spectral properties (Ex/Em: 525 nm/545 nm) and large dynamic range make ING-2 the best Na⁺ indicator for high-throughput screening applications targeting Na⁺ channels, and non-selective monovalent cation channels. ING-2 has a more physiologically relevant affinity (Kd = 20 mM) than ING-1 (Kd = 92 mM). ING-2 TMA+ Salt is the water soluble, membrane impermeable form of the sodium indicator. It can be used in lipid membrane-free systems, in liposomes or can be introduced into cells by electroporation, microinjection or other methods.
Biovision | B3138 | ING-2 TMA+ Salt DataSheet
Alternate Name/Synonyms: Sodium (Na⁺) indicator; ING-2 membrane impermeable; ING-2 tetramethylammonium (TMA+) salt; Fluorescent Sodium Na⁺ indicator
Appearance: Orange powder
Formulation:
CAS Number:
Structure Available?: TRUE
Peptide sequence:
Salt Form: TRUE
Molecular Formula: C₅₆H₈₁Cl₂N₅O₁₂
Molecular Weight: 1087
Cell-Permeable?: FALSE
Purity: ≥ 90%
Solubilities: Soluble in water
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: A membrane impermeable fluorescent sodium indicator
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