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Product Description
INH6 is a potent inhibitor of Hec1/Nek2 which regulate the mitotic spindle formation together. It causes chromosome mis-alignment, apoptosis and cell death. It inhibits proliferation of MDA-MB231, MDA-MB468, HeLa and K562 cells with IC₅₀ values of 1.7 and 2.1, 2.4, and 2.5 µM respectively.
INH6 is a potent inhibitor of Hec1/Nek2 which regulate the mitotic spindle formation together. It causes chromosome mis-alignment, apoptosis and cell death. It inhibits proliferation of MDA-MB231, MDA-MB468, HeLa and K562 cells with IC₅₀ values of 1.7 and 2.1, 2.4, and 2.5 µM respectively.
Biovision | B2907 | INH6 DataSheet
Alternate Name/Synonyms: N-[4-(2,4,6-trimethylphenyl)-1,3-thiazol-2-yl]benzamide; N-(4-mesitylthiazol-2-yl)benzamide; Hec1/Nek2 Mitotic Pathway Inhibitor II
Appearance: A crystalline solid
Formulation:
CAS Number: 1001753-24-7
Structure Available?: True
Peptide sequence:
Salt Form: false
Molecular Formula: C₁₉H₁₈N₂OS
Molecular Weight: 322.42
Cell-Permeable?: True
Purity: ≥98%
Solubilities: ~30 mg/ml in DMF in 0, ~20 mg/ml in in DMSO, ~1 mg/ml in in Ethanol
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: A potent inhibitor of Hec1/Nek2
MDL Number: MFCD04722622
PubChem CID: 7918451
SMILES: CC1=CC(=C(C(=C1)C)C2=CSC(=N2)NC(=O)C3=CC=CC=C3)C
InChi: InChI=1S/C19H18N2OS/c1-12-9-13(2)17(14(3)10-12)16-11-23-19(20-16)21-18(22)15-7-5-4-6-8-15/h4-11H,1-3H3,(H,20,21,22)
InChi Key:
