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Product Description
Nek2/Hec1 inhibitor targets the Hec1/Nek2 pathway and causes chromosome mis-alignment as well as cell death. The IC₅₀ for cytotoxicity in MDA-MB231, MDA-MB468, HeLa and K562 cell lines is 1.1 μM, 3.4 μM,1.6 μM and 1.2 μM respectively.
Nek2/Hec1 inhibitor targets the Hec1/Nek2 pathway and causes chromosome mis-alignment as well as cell death. The IC₅₀ for cytotoxicity in MDA-MB231, MDA-MB468, HeLa and K562 cell lines is 1.1 μM, 3.4 μM,1.6 μM and 1.2 μM respectively.
Biovision | B2924 | Nek2/Hec1 inhibitor DataSheet
Alternate Name/Synonyms: N-[4-(2,4-Dimethylphenyl)-2-thiazolyl]-4-pyridinecarboxamide; N-[4-(2,4-Dimethylphenyl)thiazol-2-yl]isonicotinamide
Appearance: Solid
Formulation:
CAS Number: 560103-80-2
Structure Available?: True
Peptide sequence:
Salt Form: false
Molecular Formula: C₁₇H₁₅N₃OS
Molecular Weight: 309.39
Cell-Permeable?: True
Purity: 97%
Solubilities: Soluble in in DMSO
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: An inhibitor of Nek2/Hec1
MDL Number: MFCD03384899
PubChem CID: 4363180
SMILES: O=C(C1=CC=NC=C1)NC2=NC(C3=CC=C(C)C=C3C)=CS2
InChi: InChI=1S/C17H15N3OS/c1-11-3-4-14(12(2)9-11)15-10-22-17(19-15)20-16(21)13-5-7-18-8-6-13/h3-10H,1-2H3,(H,19,20,21)
InChi Key: IBQLKKBLBXJSGU-UHFFFAOYSA-N
