Product Description
PF-04620110 is a potent and selective Acyl-CoA:diacylglycerol acyltransferase-1 (DGAT-1) inhibitor with (IC₅₀ = 19 nM).
PF-04620110 is a potent and selective Acyl-CoA:diacylglycerol acyltransferase-1 (DGAT-1) inhibitor with (IC₅₀ = 19 nM).
Biovision | B2549 | PF-04620110 DataSheet
Alternate Name/Synonyms: trans-4-[4-(4-Amino-7,8-dihydro-5-oxopyrimido[5,4-f][1,4]oxazepin-6(5H)-yl)phenyl]-cyclohexaneacetic acid; PF04620110
Appearance: Off-white solid
Formulation:
CAS Number: 1109276-89-2
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₁H₂₄N₄O₄
Molecular Weight: 396.44
Cell-Permeable?: True
Purity: ≥98%
Solubilities: >7 mg/ml in DMSO
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: A potent and selective DGAT-1 inhibitor
MDL Number:
PubChem CID: 46926360
SMILES: C1CC(CCC1CC(=O)O)C2=CC=C(C=C2)N3CCOC4=NC=NC(=C4C3=O)N
InChi: InChI=1S/C21H24N4O4/c22-19-18-20(24-12-23-19)29-10-9-25(21(18)28)16-7-5-15(6-8-16)14-3-1-13(2-4-14)11-17(26)27/h5-8,12-14H,1-4,9-11H2,(H,26,27)(H2,22,23,24)
InChi Key: GEVVQZHMFVFGLN-UHFFFAOYSA-N