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Product Description
Rilpivirine hydrochloride is a diarylpyrimidine derivative that acts as a reverse transcriptase inhibitor with antiviral activity against HIV-1. Rilpivirine is associated with a low rate of transient serum aminotransferase elevations during therapy and has been implicated in rare cases of clinically apparent acute liver injury.
Rilpivirine hydrochloride is a diarylpyrimidine derivative that acts as a reverse transcriptase inhibitor with antiviral activity against HIV-1. Rilpivirine is associated with a low rate of transient serum aminotransferase elevations during therapy and has been implicated in rare cases of clinically apparent acute liver injury.
Biovision | B2427 | Rilpivirine hydrochloride DataSheet
Alternate Name/Synonyms: TMC-278, (E)-4-((4-((4-(2-cyanovinyl)-2,6-dimethylphenyl)amino)pyrimidin-2-yl)amino)benzonitrile hydrochloride, TMC278
Appearance: White to off-white solid
Formulation:
CAS Number: 700361-47-3
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₂H₁₉ClN₆
Molecular Weight:
Cell-Permeable?: True
Purity: ≥98% by HPLC
Solubilities: DMSO
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: A second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI)
MDL Number:
PubChem CID: 11711114
SMILES: CC1=CC(=CC(=C1NC2=NC(=NC=C2)NC3=CC=C(C=C3)C#N)C)C=CC#N.Cl
InChi: InChI=1S/C22H18N6.ClH/c1-15-12-18(4-3-10-23)13-16(2)21(15)27-20-9-11-25-22(28-20)26-19-7-5-17(14-24)6-8-19;/h3-9,11-13H,1-2H3,(H2,25,26,27,28);1H/b4-3+;
InChi Key: KZVVGZKAVZUACK-BJILWQEISA-N
