Euro
USD
British Pound
NULL
Product Description
Ruxolitinib phosphate is the phosphate salt form of ruxolitinib, a potent Janus-associated kinase (JAK) inhibitor with potential antineoplastic and immunomodulating activities. Ruxolitinib specifically binds to and inhibits protein tyrosine kinases JAK 1 and 2, which may lead to a reduction in inflammation and an inhibition of cellular proliferation.
Ruxolitinib phosphate is the phosphate salt form of ruxolitinib, a potent Janus-associated kinase (JAK) inhibitor with potential antineoplastic and immunomodulating activities. Ruxolitinib specifically binds to and inhibits protein tyrosine kinases JAK 1 and 2, which may lead to a reduction in inflammation and an inhibition of cellular proliferation.
Biovision | B2631 | Ruxolitinib phosphate DataSheet
Alternate Name/Synonyms: INCB-018424 (R)-3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile phosphate INC-424 INCB018424
Appearance: White solid
Formulation:
CAS Number: 1092939-17-7
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₇H₂₁N₆O₄P
Molecular Weight: 404.37
Cell-Permeable?: True
Purity: ≥98% by HPLC
Solubilities: >30 mg/ml in DMSO
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: A potent Janus Kinase (JAK) inhibitor
MDL Number:
PubChem CID: 25127112
SMILES: N#CC[C@@H](N1N=CC(C2=C3C(NC=C3)=NC=N2)=C1)C4CCCC4.O=P(O)(O)O
InChi: InChI=1S/C17H18N6.H3O4P/c18-7-5-15(12-3-1-2-4-12)23-10-13(9-22-23)16-14-6-8-19-17(14)21-11-20-16;1-5(2,3)4/h6,8-12,15H,1-5H2,(H,19,20,21);(H3,1,2,3,4)/t15-;/m1./s1
InChi Key: JFMWPOCYMYGEDM-XFULWGLBSA-N
