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Product Description
Terbinafine hydrochloride is a selective TASK3 (TWIK-related acid-sensitive K⁺ channel 3, KCNK9, K2P9.1) activator (pEC₅₀ = 6.2). It displays >10-fold selectivity for TASK3 over TREK2, TRESK, THIK1 and TASK2. Also inhibits TWIK1 (pIC₅₀ = 5.69). Also acts as a broad-spectrum antifungal agent; inhibits fungal sterol biosynthesis by inhibition of squalene epoxidase.
erbinafine hydrochloride is a selective TASK3 (TWIK-related acid-sensitive K⁺ channel 3, KCNK9, K2P9.1) activator (pEC₅₀ = 6.2). It displays >10-fold selectivity for TASK3 over TREK2, TRESK, THIK1 and TASK2. Also inhibits TWIK1 (pIC₅₀ = 5.69). Also acts as a broad-spectrum antifungal agent; inhibits fungal sterol biosynthesis by inhibition of squalene epoxidase.
Biovision | B2657 | Terbinafine hydrochloride DataSheet
Alternate Name/Synonyms: N-[(2E)-6,6-dimethyl-2-hepten-4-yn-1-yl]-N-methyl-1-naphthalenemethanamine, monohydrochloride
Appearance: White solid
Formulation:
CAS Number: 78628-80-5
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₁H₂₅N.HCl
Molecular Weight: 327.89
Cell-Permeable?: True
Purity: ≥98%
Solubilities: >30 mg/ml in DMSO
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: A broad-spectrum antifungal agent
MDL Number: MFCD00145430
PubChem CID: 5282481
SMILES: CC(C)(C)C#CC=CCN(C)CC1=CC=CC2=CC=CC=C21.Cl
InChi: InChI=1S/C21H25N.ClH/c1-21(2,3)15-8-5-9-16-22(4)17-19-13-10-12-18-11-6-7-14-20(18)19;/h5-7,9-14H,16-17H2,1-4H3;1H/b9-5+;
InChi Key: BWMISRWJRUSYEX-SZKNIZGXSA-N
