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Product Description
Potent, reversible inhibitor of histone deacetylase. Mediates the activation of O6- methylguanine-DNA methyltransferase (MGMT). May be involved in cell cycle progression of several cell types, induces cell growth arrest at both G1 and G2/M phases. In some cases induces apoptosis.
Trichostatin A (TSA) is a potent, reversible inhibitor of histone deacetylase.
Biovision | 1606 | Trichostatin A DataSheet
Alternate Name/Synonyms: TSA, [R-(E,E)]-7-[4-(Dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide
Appearance: White solid
Formulation: N/A
CAS Number: 58880-19-6
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₇H₂₂N₂O₃
Molecular Weight: 302.4
Cell-Permeable?: Yes
Purity: ≥99%
Solubilities: DMSO (20 mg/ml) or EtOH (2 mg/ml)
Handling: Protect from air and moisture
Country of Origin: USA
Tag Line: A HDAC inhibitor
MDL Number: MFCD03848392
PubChem CID: 444732
SMILES: CC(C=C(C)C=CC(=O)NO)C(=O)C1=CC=C(C=C1)N(C)C
InChi: InChI=1S/C17H22N2O3/c1-12(5-10-16(20)18-22)11-13(2)17(21)14-6-8-15(9-7-14)19(3)4/h5-11,13,22H,1-4H3,(H,18,20)/b10-5+,12-11+/t13-/m1/s1
InChi Key: RTKIYFITIVXBLE-QEQCGCAPSA-N
