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Product Description
TVB-2640 is an oral, selective fatty acid synthase (FASN) inhibitor. It reduces hepatic de novo lipogenesis in males with metabolic abnormalities. It is being evaluated in phase 2 clinical trials to treat KRAS mutant non-small cell lung carcinomas.
TVB-2640 is an oral, selective fatty acid synthase (FASN) inhibitor. It reduces hepatic de novo lipogenesis in males with metabolic abnormalities. It is being evaluated in phase 2 clinical trials to treat KRAS mutant non-small cell lung carcinomas.
Biovision | B3125 | TVB-2640 DataSheet
Alternate Name/Synonyms: Fasn-IN-2; 4-[1-[4-cyclobutyl-2-methyl-5-(5-methyl-1H-1,2,4-triazol-3-yl)benzoyl]piperidin-4-yl]benzonitrile
Appearance: Off-white to white solid powder
Formulation:
CAS Number: 1399177-37-7
Structure Available?: TRUE
Peptide sequence:
Salt Form: FALSE
Molecular Formula: C₂₇H₂₉N₅O
Molecular Weight: 439.55
Cell-Permeable?: TRUE
Purity: ≥ 98%
Solubilities: ~80 mg/ml in DMSO or Ethanol
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: An oral, selective fatty acid synthase (FASN) inhibitor
MDL Number:
PubChem CID: 66548316
SMILES: CC1=CC(=C(C=C1C(=O)N2CCC(CC2)C3=CC=C(C=C3)C#N)C4=NNC(=N4)C)C5CCC5
InChi: InChI=1S/C27H29N5O/c1-17-14-24(22-4-3-5-22)25(26-29-18(2)30-31-26)15-23(17)27(33)32-12-10-21(11-13-32)20-8-6-19(16-28)7-9-20/h6-9,14-15,21-22H,3-5,10-13H2,1-2H3,(H,29,30,31)
InChi Key: BBGOSBDSLYHMRA-UHFFFAOYSA-N
