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Product Description
Yoda -1 is a synthetic small molecule that acts as an agonist for both human and mouse Piezo1. Characterization of Yoda1 in artificial droplet lipid bilayers shows that Yoda1 activates purified Piezo1 channels in the absence of other cellular components. Yoda1 will serve as a key tool to study Piezo1 regulation and function.
Yoda -1 is a synthetic small molecule that acts as an agonist for both human and mouse Piezo1. Characterization of Yoda1 in artificial droplet lipid bilayers shows that Yoda1 activates purified Piezo1 channels in the absence of other cellular components. Yoda1 will serve as a key tool to study Piezo1 regulation and function.
Biovision | B3335 | Yoda-1 DataSheet
Alternate Name/Synonyms: 2-[5-[[(2,6-Dichlorophenyl)methyl]thio]-1,3,4-thiadiazol-2-yl]pyrazine
Appearance: White solid
Formulation:
CAS Number: 448947-81-7
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₃H₈Cl₂N₄S₂
Molecular Weight: 355.27
Cell-Permeable?: TRUE
Purity: ≥98% by HPLC
Solubilities: >5 mg/ml DMSO
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: A piezo1 channel activator
MDL Number:
PubChem CID: 2746822
SMILES: ClC1=C(CSC2=NN=C(C3=NC=CN=C3)S2)C(Cl)=CC=C1
InChi: InChI=1S/C13H8Cl2N4S2/c14-9-2-1-3-10(15)8(9)7-20-13-19-18-12(21-13)11-6-16-4-5-17-11/h1-6H,7H2
InChi Key: BQNXBSYSQXSXPT-UHFFFAOYSA-N
