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Product Description
An orally bioavailable pan-HER tyrosine kinase inhibitor with potential antineoplastic activity. BMS-599626 inhibits human epidermal growth factor receptors (HER) HER1, HER2 and HER4, thereby inhibiting the proliferation of tumor cells that overexpress these receptors.
BMS-599626 is an orally bioavailable pan-HER tyrosine kinase inhibitor with potential antineoplastic activity. BMS-599626 inhibits human epidermal growth factor receptors (HER) HER1, HER2 and HER4, thereby inhibiting the proliferation of tumor cells that overexpress these receptors.
Biovision | 1614 | BMS-599626 DataSheet
Alternate Name/Synonyms: AC480
Appearance: Crystalline solid
Formulation: N/A
CAS Number: 873837-23-1
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₇H₂₇FN₈O₃.HCl
Molecular Weight: 567.01
Cell-Permeable?: Yes
Purity: ≥99%
Solubilities: DMSO
Handling: Protect from air and moisture
Country of Origin: USA
Tag Line: A pan-HER tyrosine kinase inhibitor
MDL Number: N/A
PubChem CID: 46930994
SMILES: CC1=C2C(=NC=NN2C=C1NC(=O)OCC3COCCN3)NC4=CC5=C(C=C4)N(N=C5)CC6=CC(=CC=C6) F.Cl
InChi: InChI=1S/C27H27FN8O3.ClH/c1-17-23(34-27(37)39-15-22-14-38-8-7-29-22)13- 36-25(17)26(30-16-32-36)33-21-5-6-24-19(10-21)11-31-35(24)12-18-3-2-4-20 (28)9-18;/h2-6,9-11,13,16,22,29H,7-8,12,14-15H2,1H3,(H,34,37)(H,30,32, 33);1H/t22-;/m0./s1
InChi Key: COUSSRGSHIJMMN-FTBISJDPSA-N
