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Product Description
Briciclib is a small molecule that suppresses cyclin D1 accumulation in cancer cells. Cyclin D, a member of the cyclin family of cell cycle regulators, plays a key role in cell cycle division and is often overexpressed in a variety of hematologic and solid tumors and is correlated with poor prognosis.
Briciclib is a small molecule that suppresses cyclin D1 accumulation in cancer cells. Cyclin D, a member of the cyclin family of cell cycle regulators, plays a key role in cell cycle division and is often overexpressed in a variety of hematologic and solid tumors and is correlated with poor prognosis.
Biovision | B1140 | Briciclib DataSheet
Alternate Name/Synonyms: [2-methoxy-5-[[(E)-2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonylmethyl]phenyl] dihydrogen phosphate
Appearance: White Solid
Formulation: N/A
CAS Number: 865783-99-9
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₉H₂₃O₁₀PS
Molecular Weight: 474.42
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (>30 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A suppressor cyclin D1 accumulation in cancer cells
MDL Number: N/A
PubChem CID: 11248490
SMILES: COC1=C(C=C(C=C1)CS(=O)(=O)C=CC2=C(C=C(C=C2OC)OC)OC)OP(=O)(O)O
InChi: 1S/C19H23O10PS/c1-25-14-10-17(27-3)15(18(11-14)28-4)7-8-31(23,24)12-13-5-6-16(26-2)19(9-13)29-30(20,21)22/h5-11H,12H2,1-4H3,(H2,20,21,22)/b8-7+
InChi Key: LXENKEWVEVKKGV-BQYQJAHWSA-N
