Product Description
Brigatinib is a highly potent and selective ALK (anaplastic lymphoma kinase) inhibitor. Potentially useful for the treatment of non-small cell lung cancer (NSCLC).
Brigatinib is a highly potent and selective ALK (anaplastic lymphoma kinase) inhibitor. Potentially useful for the treatment of non-small cell lung cancer (NSCLC).
Biovision | 9675 | Brigatinib (AP26113) DataSheet
Alternate Name/Synonyms: (2-((5-chloro-2-((4-(4-(dimethylamino)piperidin-1-yl)-2-methoxyphenyl)amino)pyrimidin-4-yl)amino)phenyl)dimethylphosphine oxide
Appearance: Light yellow to yellow solid
Formulation: N/A
CAS Number: 1197953-54-0
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₉H₃₉ClN₇O₂P
Molecular Weight: 584.09
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (>15 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A highly potent and selective ALK (anaplastic lymphoma kinase) inhibitor
MDL Number: N/A
PubChem CID: 68165256
SMILES: CN1CCN(CC1)C2CCN(CC2)C3=CC(=C(C=C3)NC4=NC=C(C(=N4)NC5=CC=CC=C5P(=O)(C)C)Cl)OC
InChi: InChI=1S/C29H39ClN7O2P/c1-35-15-17-37(18-16-35)21-11-13-36(14-12-21)22-9-10-24(26(19-22)39-2)33-29-31-20-23(30)28(34-29)32-25-7-5-6-8-27(25)40(3,4)38/h5-10,19-21H,11-18H2,1-4H3,(H2,31,32,33,34)
InChi Key: AILRADAXUVEEIR-UHFFFAOYSA-N