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Product Description
BX-471 is a potent and selective non-peptide CCR1 antagonist with a Ki of 1 nM; displays 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4.
BX-471 is a potent and selective non-peptide CCR1 antagonist with a Ki of 1 nM; displays 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4.
Biovision | B2407 | BX-471 DataSheet
Alternate Name/Synonyms: (2R)-1-[[2-[(Aminocarbonyl)amino]-4-chlorophenoxy]acetyl]-4-[(4-fluorophenyl)methyl]-2-methylpiperazine, ZK-811752
Appearance: White solid
Formulation:
CAS Number: 217645-70-0
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₁H₂₄ClFN₄O₃
Molecular Weight: 434.89
Cell-Permeable?: True
Purity: ≥98% by HPLC
Solubilities: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: A potent and selective CCR1 antagonist
MDL Number:
PubChem CID: 512282
SMILES: CC1CN(CCN1C(=O)COC2=C(C=C(C=C2)Cl)NC(=O)N)CC3=CC=C(C=C3)F
InChi: InChI=1S/C21H24ClFN4O3/c1-14-11-26(12-15-2-5-17(23)6-3-15)8-9-27(14)20(28)13-30-19-7-4-16(22)10-18(19)25-21(24)29/h2-7,10,14H,8-9,11-13H2,1H3,(H3,24,25,29)/t14-/m1/s1
InChi Key: XQYASZNUFDVMFH-CQSZACIVSA-N
