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Product Description
A synthetic peptide inhibitor that inhibits caspase-10 and related caspase activity. FMK inhibitors are irreversible and non-toxic, and can be used in both in vivo and in vitro studies. The inhibitor is designed as a methyl ester to facilitate cell permeability. (CAUTION: If the intended use is on purified or recombinant enzymes, esterase should be added to generate free carboxyl groups).
Z-AEVD-FMK is a cell-permeable, irreversible caspase-10 inhibitor.
Biovision | 1112 | Caspase-10 Inhibitor AEVD-FMK DataSheet
Alternate Name/Synonyms: Z-AEVD-FMK, Caspase-10 Inhibitor (fluoromethylketone)
Appearance: Liquid
Formulation: DMSO ( 2 mM)
CAS Number: N/A
Structure Available?: No
Peptide sequence: Z-Ala-Glu(OMe)-Val-Asp(OMe)-FMK
Salt Form: No
Molecular Formula: C₂₈H₃₉N₄O₁₀F
Molecular Weight: 610.63
Cell-Permeable?: Yes
Purity: >95% by HPLC
Solubilities: N/A
Handling: Protect from light and moisture
Country of Origin: USA
Tag Line: A caspase-10 inhibitor
MDL Number: MFCD03453601
PubChem CID: 44135225
SMILES: CC(C)C(C(=O)NC(CC(=O)OC)C(=O)CF)NC(=O)C(CCC(=O)OC)NC(=O)C(C)NC(=O)OCC1= CC=CC=C1
InChi: InChI=1S/C28H39FN4O10/c1-16(2)24(27(39)32-20(21(34)14-29)13-23(36)42-5) 33-26(38)19(11-12-22(35)41-4)31-25(37)17(3)30-28(40)43-15-18-9-7-6-8-10- 18/h6-10,16-17,19-20,24H,11-15H2,1-5H3,(H,30,40)(H,31,37)(H,32,39)(H,33, 38)
InChi Key: CHZRBQFKZDGMTP-UHFFFAOYSA-N
