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Product Description
A synthetic peptide that irreversibly inhibits caspase-2 and related caspase activity. The inhibitor is designed as a methyl ester to facilitate cell permeability. (CAUTION: If the intended use is on purified or recombinant enzymes, esterase should be added to generate free carboxyl groups).
Z-VDVD-FMK is a cell-permeable, irreversible inhibitor of caspase-2 and related caspase activity.
Biovision | 1073 | Caspase-2 Inhibitor Z-VDVAD-FMK DataSheet
Alternate Name/Synonyms: Z-VDVAD-FMK, Caspase-2 Inhibitor, Z-VDVAD-fluoromethylketone
Appearance: Liquid
Formulation: DMSO ( 2 mM)
CAS Number: N/A
Structure Available?: No
Peptide sequence: Z-Val-Asp(OMe)-Val-Ala-Asp(OMe)-FMK
Salt Form: No
Molecular Formula: C₃₂H₄₆FN₅O₁₁
Molecular Weight: 695.7
Cell-Permeable?: Yes
Purity: >98% by HPLC
Solubilities: N/A
Handling: Protect from light and moisture
Country of Origin: USA
Tag Line: A caspase-2 inhibitor
MDL Number: MFCD03452881
PubChem CID: 44135215
SMILES: CC(C)C(C(=O)NC(C)C(=O)NC(CC(=O)OC)C(=O)CF)NC(=O)C(CC(=O)OC)NC(=O)C(C(C)C)NC(=O)OCC1=CC=CC=C1
InChi: InChI=1S/C32H46FN5O11/c1-17(2)26(30(44)34-19(5)28(42)35-21(23(39)15-33)13-24(40)47-6)37-29(43)22(14-25(41)48-7)36-31(45)27(18(3)4)38-32(46)49-16-20-11-9-8-10-12-20/h8-12,17-19,21-22,26-27H,13-16H2,1-7H3,(H,34,44)(H,35,42)(H,36,45)(H,37,43)(H,38,46)
InChi Key: ANTIWMNLIROOQF-UHFFFAOYSA-N
