Product Description
Caspase-3/7 inhibitor is a potent, cell-permeable, specific, and reversible inhibitor of caspase-3 (Ki = 60 nM) and caspase-7 (Ki = 170 nM). It acts as a weaker inhibitor of caspase-9 (Ki = 3.1 µM).
Caspase-3/7 inhibitor is a potent, cell-permeable, specific, and reversible inhibitor of caspase-3 (Ki = 60 nM) and caspase-7 (Ki = 170 nM). It acts as a weaker inhibitor of caspase-9 (Ki = 3.1 µM).
Biovision | 2780 | Caspase-3/7 Inhibitor DataSheet
Alternate Name/Synonyms: 5-[(2S)-2-(methoxymethyl)pyrrolidin-1-yl]sulfonyl-1H-indole-2,3-dione
Appearance: Yellow solid
Formulation: N/A
CAS Number: 220509-74-0
Structure Available?: Y
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₄H₁₆N₂O₅S
Molecular Weight: 324.4
Cell-Permeable?: Y
Purity: ≥97% by HPLC
Solubilities: DMSO (~ 200 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A specific caspase-3/7 inhibitor
MDL Number: MFCD22581511
PubChem CID: 9840223
SMILES: COCC1CCCN1S(=O)(=O)C2=CC3=C(C=C2)NC(=O)C3=O
InChi: InChI=1S/C14H16N2O5S/c1-21-8-9-3-2-6-16(9)22(19,20)10-4-5-12-11(7-10)13(17)14(18)15-12/h4-5,7,9H,2-3,6,8H2,1H3,(H,15,17,18)/t9-/m0/s1
InChi Key: SLQMNVJNDYLJSF-VIFPVBQESA-N