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Product Description
A synthetic peptide that irreversibly inhibits caspase-5 and related caspase activity. The inhibitor is designed as a methyl ester to facilitate cell permeability. (CAUTION: If the intended use is on purified or recombinant enzymes, esterase should be added to generate free carboxyl groups).
Z-ATAD-FMK is a cell-permeable, irreversible caspase-5 inhibitor.
Biovision | 1100 | Caspase-5 Inhibitor Z-WEHD-FMK DataSheet
Alternate Name/Synonyms: Z-WEHD-FMK, Caspase-5 Inhibitor (fluoromethylketone)
Appearance: Liquid
Formulation: DMSO (2 mM)
CAS Number: N/A
Structure Available?: No
Peptide sequence: Z-Trp-Glu(OMe)-His-Asp(OMe)-FMK
Salt Form: No
Molecular Formula: C₃₇H₄₂FN₇O₁₁
Molecular Weight: 763.78
Cell-Permeable?: yes
Purity: >99% by HPLC
Solubilities: N/A
Handling: Protect from light and moisture
Country of Origin: USA
Tag Line: A caspase-5 inhibitor
MDL Number: MFCD03453283
PubChem CID: 44134610
SMILES: COC(=O)CCC(C(=O)NC(CC1=CN=CN1)C(=O)NC(CC(=O)OC)C(=O)CF)NC(=O)C(CC2=CNC3= CC=CC=C32)NC(=O)OCC4=CC=CC=C4
InChi: InChI=1S/C37H42FN7O10/c1-53-32(47)13-12-27(34(49)44-30(15-24-19-39-21- 41-24)36(51)43-28(31(46)17-38)16-33(48)54-2)42-35(50)29(14-23-18-40-26- 11-7-6-10-25(23)26)45-37(52)55-20-22-8-4-3-5-9-22/h3-11,18-19,21,27-30, 40H,12-17,20H2,1-2H3,(H,39,41)(H,42,50)(H,43,51)(H,44,49)(H,45,52)
InChi Key: NLZNSSWGRVBWIX-UHFFFAOYSA-N
