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Product Description
CEP-18770 is a reversible P2 threonine boronic acid inhibitor of the chymotrypsin-like activity of the proteasome. Displays anti-multimyeloma (MM) effect.
CEP-18770 is a reversible P2 threonine boronic acid inhibitor of the chymotrypsin-like activity of the proteasome. Displays anti-multimyeloma (MM) effect.
Biovision | 2433 | CEP-18770 DataSheet
Alternate Name/Synonyms: [(1R)-1-[[(2S,3R)-3-Hydroxy-2-[[(6-phenylpyridin-2-yl)carbonyl]amino]-1-oxobutyl]amino]-3-methylbutyl]boronic acid
Appearance: Off-white solid
Formulation: N/A
CAS Number: 847499-27-8
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₁H₂₈BN₃O₅
Molecular Weight: 413.28
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (>70 mg/ml) or EtOH (>70 mg/ml)
Handling: Protect from air and mositure
Country of Origin: USA
Tag Line: A potent proteosome inhibitor
MDL Number: N/A
PubChem CID: 24800541
SMILES: B(C(CC(C)C)NC(=O)C(C(C)O)NC(=O)C1=CC=CC(=N1)C2=CC=CC=C2)(O)O
InChi: InChI=1S/C21H28BN3O5/c1-13(2)12-18(22(29)30)24-21(28)19(14(3)26)25-20(27)17-11-7-10-16(23-17)15-8-5-4-6-9-15/h4-11,13-14,18-19,26,29-30H,12H2,1-3H3,(H,24,28)(H,25,27)/t14-,18+,19+/m1/s1
InChi Key: SJFBTAPEPRWNKH-CCKFTAQKSA-N
