Product Description
Cell-permeable. A histone deacetylase (HDAC) inhibitor (Ki values are 0.41, 0.75, >100 and >100 µM for HDAC1, HDAC3, HDAC6 and HDAC8 respectively). Displays significant antitumor activity in vitro and in vivo against a broad spectrum of murine and human tumor models.
CI-994 is a cell-permeable, histone deacetylase (HDAC) inhibitor (Ki values are 0.41, 0.75, >100 and >100 µM for HDAC1, HDAC3, HDAC6 and HDAC8 respectively). Displays significant antitumor activity in vitro and in vivo against a broad spectrum of murine and human tumor models.
Biovision | 1742 | CI-994 DataSheet
Alternate Name/Synonyms: 4-(Acetylamino)-N-(2-aminophenyl)benzamide, Acetyldinaline, Gö 5549, PD 123654
Appearance: White to off-white solid
Formulation: N/A
CAS Number: 112522-64-2
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₅H₁₅N₃O₂
Molecular Weight: 269.3
Cell-Permeable?: Yes
Purity: ≥99% by HPLC
Solubilities: DMSO (60 mg/ml)
Handling: Protect from air and moisture
Country of Origin: USA
Tag Line: A HDAC inhibitor
MDL Number: MFCD00866266
PubChem CID: 2746
SMILES: CC(=O)NC1=CC=C(C=C1)C(=O)NC2=CC=CC=C2N
InChi: InChI=1S/C15H15N3O2/c1-10(19)17-12-8-6-11(7-9-12)15(20)18-14-5-3-2-4-13(14)16/h2-9H,16H2,1H3,(H,17,19)(H,18,20)
InChi Key: VAZAPHZUAVEOMC-UHFFFAOYSA-N