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Product Description
CID-1067700 is a potent, and competitive, Ras-related GTPase inhibitor. It binds the nucleotide binding pocket of Rab7 with a Ki value of 13 nM, preventing BODIPY-linked GTP and GDP binding with EC₅₀ values of 11.2 and 21 nM, respectively
CID-1067700 is a potent, and competitive, Ras-related GTPase inhibitor. It binds the nucleotide binding pocket of Rab7 with a Ki value of 13 nM, preventing BODIPY-linked GTP and GDP binding with EC₅₀ values of 11.2 and 21 nM, respectively
Biovision | 2688 | CID-1067700 DataSheet
Alternate Name/Synonyms: 2-(Benzoylcarbamothioylamino)-5,5-dimethyl-4,7-dihydrothieno[2,3-c]pyran-3-carboxylic acid, 2-[[(Benzoylamino)thioxomethyl]amino]-4,7-dihydro-5,5-dimethyl-5H-thieno[2,3-c]pyran-3-carboxylic acid, CID-1067700, CID1067700, SID57578339; ML282
Appearance: White to off-white solid
Formulation: N/A
CAS Number: 314042-01-8
Structure Available?: Y
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₈H₁₈N₂O₄S₂
Molecular Weight: 390.48
Cell-Permeable?: Yes
Purity: ≥95% by HPLC
Solubilities: DMSO (~ 10 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A potent Ras-related GTPase inhibitor
MDL Number: N/A
PubChem CID: 1067700
SMILES: O=C(C1=C(NC(NC(C2=CC=CC=C2)=O)=S)SC3=C1CC(C)(C)OC3)O
InChi: InChI=1S/C18H18N2O4S2/c1-18(2)8-11-12(9-24-18)26-15(13(11)16(22)23)20-17(25)19-14(21)10-6-4-3-5-7-10/h3-7H,8-9H2,1-2H3,(H,22,23)(H2,19,20,21,25)
InChi Key: ATSWBWHRHAQVFM-UHFFFAOYSA-N
