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Product Description
CID-5951923 is an Inhibitor of Krüppel-like factor 5 (KLF5) transcription factor (IC₅₀ = 2.3 μM). Significantly reduces endogenous KLF5 protein levels and decreases viability of colon cancer cells, without affecting the nontransformed intestinal epithelial cells IEC-6.
CID-5951923 is an Inhibitor of Krüppel-like factor 5 (KLF5) transcription factor (IC₅₀ = 2.3 μM). Significantly reduces endogenous KLF5 protein levels and decreases viability of colon cancer cells, without affecting the nontransformed intestinal epithelial cells IEC-6.
Biovision | 2690 | CID-5951923 DataSheet
Alternate Name/Synonyms: 2-[Methyl(tetrahydro-1,1-dioxido-3-thienyl)amino]-2-oxoethyl (E)-3-(3-nitrophenyl)prop-2-enoate
Appearance: Off-white solid
Formulation: N/A
CAS Number: 749872-43-3
Structure Available?: Y
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₆H₁₈N₂O₇S
Molecular Weight: 382.39
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (~ 30 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A Krüppel-like factor 5 (KLF5) transcription factor inhibitor
MDL Number: MFCD04796932
PubChem CID: 5951923
SMILES: CN(C1CCS(=O)(=O)C1)C(=O)COC(=O)C=CC2=CC(=CC=C2)[N+](=O)[O-]
InChi: InChI=1S/C16H18N2O7S/c1-17(14-7-8-26(23,24)11-14)15(19)10-25-16(20)6-5-12-3-2-4-13(9-12)18(21)22/h2-6,9,14H,7-8,10-11H2,1H3/b6-5+
InChi Key: URVRJYLSUVXWBC-AATRIKPKSA-N
