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Product Description
An adiponectin receptor (AdipoR) agonist. Binds to AdipoR1 and AdipoR2 less potent than AdipoRon (Cat. Nos. 2565 & 2572). Activates 5'-adenosine monophosphate-activated protein kinase (AMPK) in cultured mammalian cells .Improves diabetes, glucose and lipid metabolism and insulin sensitivity in cultured cells and in mice by AdipoR-dependent mechanisms.
Compound 112254 is a adiponectin receptor (AdipoR) agonist. Binds to AdipoR1 and AdipoR2 less potent than AdipoRon (Cat. Nos. 2565 & 2572). Activates 5'-adenosine monophosphate-activated protein kinase (AMPK) in cultured mammalian cells .Improves diabetes, glucose and lipid metabolism and insulin sensitivity.
Biovision | 2573 | Compound 112254 DataSheet
Alternate Name/Synonyms: 4-(tert-Butyl)-N-(3-(4-(4-methoxybenzyl)piperazin-1-yl)-3-oxopropyl)benzamide
Appearance: White solid
Formulation: N/A
CAS Number: N/A
Structure Available?: Y
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₆H₃₅N₃O₃
Molecular Weight: 437.57
Cell-Permeable?: Yes
Purity: ≥98% by NMR
Solubilities: DMSO or EtOH
Handling: Protect from air and light
Country of Origin: USA
Tag Line: An adiponectin receptor agonist
MDL Number: N/A
PubChem CID: N/A
SMILES: CC(C1=CC=C(C=C1)CNCCCN2CCN(CC3=CC=C(OC)C=C3)CC2)(C)C
InChi: InChI=1S/C26H39N3O/c1-26(2,3)24-10-6-22(7-11-24)20-27-14-5-15-28-16-18-29(19-17-28)21-23-8-12-25(30-4)13-9-23/h6-13,27H,5,14-21H2,1-4H3
InChi Key: LUEVKMSIYRYUKC-UHFFFAOYSA-N
