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Product Description
α-Cyano-4-hydroxycinnamate (4-CIN) is a monocarboxylate transporter (MCT) inhibitor. Displays antitumor and antiangiogenic activity in gliomas in vivo; decreases glycolytic metabolism, migration, and invasion in U251 cells. Also blocks lactate efflux from glioma cells and sensitizes cells to irradiation.
α-Cyano-4-hydroxycinnamate (4-CIN) is a monocarboxylate transporter (MCT) inhibitor. Displays antitumor and antiangiogenic activity in gliomas in vivo; decreases glycolytic metabolism, migration, and invasion in U251 cells. Also blocks lactate efflux from glioma cells and sensitizes cells to irradiation.
Biovision | B2162 | α-Cyano-4-hydroxycinnamic acid DataSheet
Alternate Name/Synonyms: α-CCA; 4-HCCA; CHCA; NSC173138; 4-CIN
Appearance: Yellow solid
Formulation: N/A
CAS Number: 28166-41-8
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₀H₇NO₃
Molecular Weight: 189.17
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (10 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A monocarboxylate transporter (MCT) inhibitor
MDL Number: MFCD00004204
PubChem CID: 5328791
SMILES: C1=CC(=CC=C1C=C(C#N)C(=O)O)O
InChi: InChI=1S/C10H7NO3/c11-6-8(10(13)14)5-7-1-3-9(12)4-2-7/h1-5,12H,(H,13,14)/b8-5+
InChi Key: AFVLVVWMAFSXCK-VMPITWQZSA-N
