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Product Description
A potent, cell-permeable, and irreversible inhibitor of calpain II (k₂ = 28,900 M⁻¹s⁻¹). Also acts as an inhibitor of cathepsin L (k₂= 680,000 M⁻¹s⁻¹).
Z-LLY-FMK is a potent, cell-permeable, and irreversible inhibitor of calpain II (k₂ = 28,900 M⁻¹s⁻¹). Also acts as an inhibitor of cathepsin L (k₂= 680,000 M⁻¹s⁻¹).
Biovision | 1125 | EZSolution™ Calpain Inhibitor, Z-LLY-FMK DataSheet
Alternate Name/Synonyms: Z-LLY-FMK, Calpain Inhibitor(fluoromethylketone)
Appearance: Liquid
Formulation: DMSO (10 mM)
CAS Number: 133410-84-1
Structure Available?: No
Peptide sequence: Z-Leu-Leu-Tyr-FMK
Salt Form: No
Molecular Formula: C₃₀H₄₀FN₃O₆
Molecular Weight: 557.7
Cell-Permeable?: Yes
Purity: >95% by HPLC
Solubilities: N/A
Handling: Protect from light and moisture
Country of Origin: USA
Tag Line: A cathepsin B & L and Calpain inhibitor
MDL Number: N/A
PubChem CID: 16760337
SMILES: CC(C)CC(C(=O)NC(CC1=CC=C(C=C1)O)C(=O)CF)NC(=O)C(CC(C)C)NC(=O)OCC2=CC=CC=C2
InChi: InChI=1S/C30H40FN3O6/c1-19(2)14-25(28(37)32-24(27(36)17-31)16-21-10-12- 23(35)13-11-21)33-29(38)26(15-20(3)4)34-30(39)40-18-22-8-6-5-7-9-22/h5- 13,19-20,24-26,35H,14-18H2,1-4H3,(H,32,37)(H,33,38)(H,34,39)
InChi Key: JCRSHQCFRMCMOC-UHFFFAOYSA-N
