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Product Description
FIPI is a potent and selective phospholipase D (PLD) inhibitor. FIPI inhibits both PLD1 (IC50 = 25 nM) and PLD2 (IC₅₀ = 20 nM); prevents PLD regulation of F-actin cytoskeleton reorganization, cell spreading, and chemotaxis.
FIPI is a potent and selective phospholipase D (PLD) inhibitor. FIPI inhibits both PLD1 (IC50 = 25 nM) and PLD2 (IC₅₀ = 20 nM); prevents PLD regulation of F-actin cytoskeleton reorganization, cell spreading, and chemotaxis.
Biovision | B2372 | FIPI (free base) DataSheet
Alternate Name/Synonyms: N-[2-[4-(2,3-Dihydro-2-oxo-1H-benzimidazol-1-yl)-1-piperidinyl]ethy]-5-fluoro-1H-indole-2-carboxamide
Appearance: White to off-white solid
Formulation:
CAS Number: 939055-18-2
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: N/A
Molecular Formula: C₂₃H₂₄FN₅O₂
Molecular Weight: 421.48
Cell-Permeable?: TRUE
Purity: ≥98% by HPLC
Solubilities: >25 mg/ml in DMSO
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: A potent and selective phospholipase D (PLD) inhibitor
MDL Number:
PubChem CID: 16739265
SMILES: C1CN(CCC1N2C3=CC=CC=C3NC2=O)CCNC(=O)C4=CC5=C(N4)C=CC(=C5)F
InChi: InChI=1S/C23H24FN5O2/c24-16-5-6-18-15(13-16)14-20(26-18)22(30)25-9-12-28-10-7-17(8-11-28)29-21-4-2-1-3-19(21)27-23(29)31/h1-6,13-14,17,26H,7-12H2,(H,25,30)(H,27,31)
InChi Key: LHABRXRGDLASIH-UHFFFAOYSA-N
