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Product Description
FITC-D(OMe)E(OMe)VD(OMe)-FMK is a fluorescein isothiocyanate (FITC) conjugate of the cell- permeable caspase inhibitor D(OMe)E(OMe)VD(OMe)-FMK that acts as an in situ marker for detection of caspase-3 in living cells. FITC-D(OMe)E(OMe)VD(OMe)-FMK is nontoxic, and irreversibly binds to activated caspase-3 in apoptotic cells. The bound marker is localized by fluorescence detection
FITC-D(OMe)E(OMe)VD(OMe)-FMK is a fluorescein isothiocyanate (FITC) conjugate of the cell- permeable caspase inhibitor D(OMe)E(OMe)VD(OMe)-FMK that acts as an in situ marker for detection of caspase-3 in living cells. FITC-D(OMe)E(OMe)VD(OMe)-FMK is nontoxic, and irreversibly binds to activated caspase-3 in apoptotic cells. The bound marker is localized by fluorescence detection
Biovision | 9499 | FITC-DEVD-FMK DataSheet
Alternate Name/Synonyms: FITC-Asp-Glu-Val-Asp-fluoromethyl ketone; FITC-D(OMe)-E(OMe)-VD(OMe)-FMK
Appearance: Liquid
Formulation: A 0.6 mM solution in DMSO
CAS Number: N/A
Structure Available?: Yes
Peptide sequence: FITC-D(OMe)-E(OMe)-VD(OMe)-FMK
Salt Form: No
Molecular Formula: C₄₃H₄₆FN₅O₁₅S
Molecular Weight: 923.91
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: N/A
Handling: Protect from air and moisture
Country of Origin: USA
Tag Line: A caspase-3 in situ marker
MDL Number: N/A
PubChem CID: N/A
SMILES: O=C(OC)CC[C@H](NC([C@@H](N/C(S)=N/C1=CC=C(C2(C3=CC=C(O)C=C3OC4=C2C=CC(O)=C4)OC5=O)C5=C1)CC(OC)=O)=O)C(N[C@@H](C(C)C)C(N[C@H](C(CF)=O)CC(OC)=O)=O)=O
InChi: InChI=1S/C43H46FN5O15S/c1-20(2)37(40(58)47-29(31(52)19-44)17-35(54)61-4)49-38(56)28(12-13-34(53)60-3)46-39(57)30(18-36(55)62-5)48-42(65)45-21-6-9-25-24(14-21)41(59)64-43(25)26-10-7-22(50)15-32(26)63-33-16-23(51)8-11-27(33)43/h6-11,14-16,20,28-30,37,50-51H,12-13,17-19H2,1-5H3,(H,46,57)(H,47,58)(H,49,56)(H2,45,48,65)/t28-,29-,30-,37-/m0/s1
InChi Key: GRXLYHYCYCURGM-OWBZZYPYSA-N
