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Product Description
Cell-permeable. A potent antagonist of the Hedgehog (Hh) signaling pathway (IC₅₀ = 70 nM).
Hh Signaling Pathway Antagonist is a potent antagonist of the Hedgehog (Hh) signaling pathway (IC₅₀ = 70 nM).
Biovision | 1659 | Hh Signaling Pathway Antagonist DataSheet
Alternate Name/Synonyms: N-[4-Chloro-3-(trifluoromethyl)phenyl]-N’-[[3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl]methyl-urea
Appearance: White to off-white solid
Formulation: N/A
CAS Number: 330796-24-2
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₃H₁₅ClF₄N₄O₂
Molecular Weight: 490.84
Cell-Permeable?: Yes
Purity: ≥97% by HPLC
Solubilities: DMSO
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A hedgehog (Hh) signaling pathway inhibitor
MDL Number: N/A
PubChem CID: 9913498
SMILES: C1=CC=C2C(=C1)C(=O)N(C(=N2)CNC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F)C4=CC=C(C=C4)F
InChi: InChI=1S/C23H15ClF4N4O2/c24-18-10-7-14(11-17(18)23(26, 27)28)30-22(34)29-12-20-31-19-4-2-1-3-16(19)21(33)32(20)15-8-5-13(25)6- 9-15/h1-11H,12H2,(H2,29,30,34)
InChi Key: NYOXUHUPXGFHIB-UHFFFAOYSA-N
