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Product Description
A benzimidazole analog that acts as a potent and selective inhibitor of IKK-ε kinase (IC₅₀ = 40 nM); displays >125-fold selectivity over IKK-α and IKK-β.
IKK-ε Kinase Inhibitor II is a benzimidazole analog that acts as a potent and selective inhibitor of IKK-ε kinase (IC₅₀ = 40 nM); displays >125-fold selectivity over IKK-α and IKK-β.
Biovision | 1811 | IKK-ε Kinase Inhibitor II DataSheet
Alternate Name/Synonyms: 5-(5,6-dimethoxy-1H-benzimidazol-1-yl)-3-[[2-(methylsulfonyl)phenyl]methoxy]-2-thiophenecarbonitrile
Appearance: Crystalline solid
Formulation: N/A
CAS Number: 862812-98-4
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₂H₁₉N₃O₅S₂
Molecular Weight: 469.53
Cell-Permeable?: Yes
Purity: ≥97% by HPLC
Solubilities: DMSO
Handling: Protect from air and light
Country of Origin: USA
Tag Line: An IKK-ε kinase inhibitor
MDL Number: N/A
PubChem CID: 11626927
SMILES: COC1=C(C=C2C(=C1)N=CN2C3=CC(=C(S3)C#N)OCC4=CC=CC=C4S(=O)(=O)C)OC
InChi: InChI=1S/C22H19N3O5S2/c1-28-17-8-15-16(9-18(17)292)25(13-24-15)22-10-19(20(11-23)31-22)30-12-14-6-4-5-7-21(14)32(3,26)27/h4-10,13H,12H2,1-3H3
InChi Key: LDTAHRLHGHFHKP-UHFFFAOYSA-N
