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Product Description
Imidapril is a prodrug for the active metabolite imidaprilat, an angiotensin-converting enzyme (ACE) inhibitor that suppresses the conversion of angiotensin I to angiotensin II (IC₅₀ = 2.6 nM), thereby preventing vasoconstriction and decreasing aldosterone secretion by the adrenal cortex which leads to an increase in sodium excretion and subsequently increases water outflow.
Imidapril is a prodrug for the active metabolite imidaprilat, an angiotensin-converting enzyme (ACE) inhibitor that suppresses the conversion of angiotensin I to angiotensin II (IC₅₀ = 2.6 nM), thereby preventing vasoconstriction and decreasing aldosterone secretion by the adrenal cortex which leads to an increase in sodium excretion and subsequently increases water outflow.
Biovision | B2135 | Imidapril hydrochloride DataSheet
Alternate Name/Synonyms: (4S)-3-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1-methyl-2-oxo-4-imidazolidinecarboxylic acid hydrochloride, Novaloc, TA 6366, Tanapril
Appearance: White to off-white solid
Formulation: N/A
CAS Number: 89396-94-1
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₀H₂₇N₃O₆ · HCl
Molecular Weight: 441.91
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: H₂O (>5 mg/ml)
Handling: Protect from air and moisture
Country of Origin: USA
Tag Line: A potent angiotensin converting-Enzyme (ACE) inhibitor
MDL Number: MFCD00923828
PubChem CID: 5485193
SMILES: CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2C(CN(C2=O)C)C(=O)
InChi: InChI=1S/C20H27N3O6.ClH/c1-4-29-19(27)15(11-10-14-8-6-5-7-9-14)21-13(2)17(24)23-16(18(25)26)12-22(3)20(23)28;/h5-9,13,15-16,21H,4,10-12H2,1-3H3,(H,25,26);1H/t13-,15-,16-;/m0./s1
InChi Key: LSLQGMMMRMDXHN-GEUPQXMHSA-N
