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Product Description
Antibiotic that acts as a potent and selective calcium ionophore; more effective than A23187. Ionomycin binds Ca2+ in the 7.0-9.5 pH range with the resulting complex exhibiting intense UV absorption. Ionomycin induces apoptosis in immature B cell lines and in cultured embryonic rat cortical neurons. More mature B cell lines do not undergo apoptosis, but are arrested in the G1 phase of the cell cycle.
Ionomycin is a n antibiotic that acts as a potent and selective calcium ionophore; more effective than A23187. Ionomycin binds Ca2+ in the 7.0-9.5 pH range with the resulting complex exhibiting intense UV absorption.
Biovision | 1565 | Ionomycin (free acid) DataSheet
Alternate Name/Synonyms:
Appearance: Waxy solid
Formulation: N/A
CAS Number: 56092-81-0
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₄₁H₇₂O₉
Molecular Weight: 709.02
Cell-Permeable?: Yes
Purity: ≥97%
Solubilities: DMSO
Handling: Protect from light and moisture
Country of Origin: USA
Tag Line: A calcium ionophore
MDL Number: MFCD06798385
PubChem CID: 6912226
SMILES: CC(CCC(=O)O)CC(C)CC(C)C(=O)C=C(C(C)CC(C)CC=CC(C)C(C(C)C(CC1CCC(O1)(C)C2CCC(O2)(C)C(C)O)O)O)O
InChi: InChI=1S/C41H72O9/c1-25(21-29(5)34(43)24-35(44)30(6)22-27(3)20-26(2)14-15-38(46)47)12-11-13-28(4)39(48)31(7)36(45)23-33-16-18-41(10,49-33)37-17-19-40(9,50-37)32(8)42/h11,13,24-33,36-37,39,42-43,45,48H,12, 14-23H2,1-10H3,(H,46,47)/b13-11+,34-24-/t25-,26-,27+,28-,29-,30+,31+,32-,33+,36+,37-,39-,40+,41+/m1/s1
InChi Key: PGHMRUGBZOYCAA-ADZNBVRBSA-N
