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Product Description
L-DON is a glutamine antagonist produced naturally by Streptomyces; it inhibits several glutamine-dependent enzyme pathways as well as acts as an inhibitor of the mitochondrial enzyme, glutaminase (GLS), the primary producer of neuronal glutamate.
L-DON is a glutamine antagonist produced naturally by Streptomyces; it inhibits several glutamine-dependent enzyme pathways as well as acts as an inhibitor of the mitochondrial enzyme, glutaminase (GLS), the primary producer of neuronal glutamate.
Biovision | B1955 | L-DON DataSheet
Alternate Name/Synonyms: H-Glu(diazomethylketone)-OH, 6-Diazo-5-oxo-L-2-aminohexanoic acid; 6-Diazo-5-oxo-L-norleucine
Appearance: Yellow solid
Formulation: N/A
CAS Number: 157-03-9
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₆H₉N₃O₃
Molecular Weight: 171.16
Cell-Permeable?: Yes
Purity: ≥95% by TLC
Solubilities: PBS (pH 7.2, 10 mg/ml)
Handling: Protect from air and moisture
Country of Origin: USA
Tag Line: A glutamine antagonist
MDL Number: MFCD00037218
PubChem CID: 5359375
SMILES: C(CC(=C[N+]#N)[O-])C(C(=O)O)N
InChi: InChI=1S/C6H9N3O3/c7-5(6(11)12)2-1-4(10)3-9-8/h3,5H,1-2,7H2,(H-,10,11,12)/b4-3-/t5-/m0/s1
InChi Key: MKZFABOMIIHLIT-XUELKZDXSA-N
