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Product Description
Loperamide is an antidiarrheal agent that acts as a non-selective Ca²⁺ channel blocker. At nanomolar concentrations (Ki = 2 nM), Loperamide binds to µ-opioid receptors. Also acts as an mTOR-independent autophagy enhancer.
Loperamide is an antidiarrheal agent that acts as a non-selective Ca²⁺ channel blocker. At nanomolar concentrations (Ki = 2 nM), Loperamide binds to µ-opioid receptors. Also acts as an mTOR-independent autophagy enhancer.
Biovision | 2683 | Loperamide hydrochloride DataSheet
Alternate Name/Synonyms: 4-(4-Chlorophenyl)-4-hydroxy-N,N-dimethyl-α,α-diphenyl-1-piperidinebutanamide hydrochloride
Appearance: White solid
Formulation: N/A
CAS Number: 34552-83-5
Structure Available?: Y
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₉H₃₃ClN₂O₂.HCl
Molecular Weight: 513.51
Cell-Permeable?: Yes
Purity: ≥98% by titration
Solubilities: DMSO (>20 mg/ml) or EtOH (>20 mg/ml)
Handling: Protect from air and moisture
Country of Origin: USA
Tag Line: A calcium channel blocker and an autophagy inducer
MDL Number: MFCD00058581
PubChem CID: 71420
SMILES: CN(C)C(=O)C(CCN1CCC(CC1)(C2=CC=C(C=C2)Cl)O)(C3=CC=CC=C3)C4=CC=CC=C4.Cl
InChi: nChI=1S/C29H33ClN2O2.ClH/c1-31(2)27(33)29(24-9-5-3-6-10-24,25-11-7-4-8-12-25)19-22-32-20-17-28(34,18-21-32)23-13-15-26(30)16-14-23;/h3-16,34H,17-22H2,1-2H3;1H
InChi Key: PGYPOBZJRVSMDS-UHFFFAOYSA-N
