Product Description
A protease inhibitor with high specificity for HIV-1 protease. Inhibition of HIV-1 protease (responsible for protein cleavage), results in selectively inhibiting the cleavage of HIV gag and gag-pol polyproteins, thereby preventing viral maturation.
Lopinavir is a HIV protease inhibitor
Biovision | 2241 | Lopinavir DataSheet
Alternate Name/Synonyms: (2S)-N-[(2S,4S,5S)-5-[2-(2,6-dimethylphenoxy)acetamido]-4-hydroxy-1,6-diphenylhexan-2-yl]-3-methyl-2-(2-oxo-1,3-diazinan-1-yl)butanamide
Appearance: White to off-white solid
Formulation: N/A
CAS Number: 192725-17-0
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₃₇H₄₈N₄O₅
Molecular Weight: 628.81
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO
Handling: Protect from light and moisture
Country of Origin: USA
Tag Line: A HIV-1 protease inhibitor
MDL Number: MFCD04973616
PubChem CID: 92727
SMILES: CC1=C(C(=CC=C1)C)OCC(=O)NC(CC2=CC=CC=C2)C(CC(CC3=CC=CC=C3)NC(=O)C(C(C)C)N4CCCNC4=O)O
InChi: InChI=1S/C37H48N4O5/c1-25(2)34(41-20-12-19-38-37(41)45)36(44)39-30(21-28-15-7-5-8-16-28)23-32(42)31(22-29-17-9-6-10-18-29)40-33(43)24-46-35-26(3)13-11-14-27(35)4/h5-11,13-18,25,30-32,34,42H,12,19-24H2,1-4H3,(H,38,45)(H,39,44)(H,40,43)/t30-,31-,32-,34-/m0/s1
InChi Key: KJHKTHWMRKYKJE-SUGCFTRWSA-N