Euro
USD
British Pound
NULL
Product Description
A guanosine derivative that acts as a selective ligand for Toll-like receptor 7 (TLR7) via IFN. Activates natural killer cells and primes cytolytic precursor cells for activation by IL-2.
Loxoribine is a guanosine derivative that acts as a selective ligand for Toll-like receptor 7 (TLR7) via IFN. Activates natural killer cells and primes cytolytic precursor cells for activation by IL-2.
Biovision | 2003 | Loxoribine DataSheet
Alternate Name/Synonyms: 7-Allyl-8-oxoguanosine ; RWJ21757
Appearance: White solid
Formulation: N/A
CAS Number: 121288-39-9
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₃H₁₇N₅O₆
Molecular Weight: 339.3
Cell-Permeable?: Yes
Purity: ≥97% by HPLC
Solubilities: DMSO (30 mg/ml) or water (10 mg/ml)
Handling: Protect from light and moisture
Country of Origin: USA
Tag Line: A selective TLR7 ligand
MDL Number: MFCD00867591
PubChem CID: 60737
SMILES: C=CCN1C2=C(NC(=NC2=O)N)N(C1=O)C3C(C(C(O3)CO)O)O
InChi: InChI=1S/C13H17N5O6/c1-2-3-17-6-9(15-12(14)16-10(6)22)18(13(17)23)11-8 (21)7(20)5(4-19)24-11/h2,5,7-8,11,19-21H,1,3-4H2,(H3,14,15,16,22)/t5-, 7-,8-,11-/m1/s1
InChi Key: VDCRFBBZFHHYGT-IOSLPCCCSA-N
