Product Description
LY404187 is a selective, potent and centrally active positive allosteric modulator of AMPA receptors. It preferentially acts at recombinant human homomeric GluR2 and GluR4 versus GluR1 and GluR3 AMPA receptors. LY404187 does not display any activity at human recombinant kinate receptors.
LY404187 is a selective, potent and centrally active positive allosteric modulator of AMPA receptors. It preferentially acts at recombinant human homomeric GluR2 and GluR4 versus GluR1 and GluR3 AMPA receptors. LY404187 does not display any activity at human recombinant kinate receptors.
Biovision | 2698 | LY404187 DataSheet
Alternate Name/Synonyms: LY-404187; N-[2-(4'-cyanobiphenyl-4-yl)propyl]propane-2-sulfonamide
Appearance: Crystalline solid
Formulation: N/A
CAS Number: 211311-95-4
Structure Available?: Y
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₉H₂₂N₂O₂S
Molecular Weight: 342.46
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A potent and centrally active positive allosteric modulator of AMPA receptors
MDL Number: N/A
PubChem CID: 9928016
SMILES: CC(C)S(=O)(=O)NCC(C)C1=CC=C(C=C1)C2=CC=C(C=C2)C#N
InChi: InChI=1S/C19H22N2O2S/c1-14(2)24(22,23)21-13-15(3)17-8-10-19(11-9-17)18-6-4-16(12-20)5-7-18/h4-11,14-15,21H,13H2,1-3H3
InChi Key: HOQAVGZLYRYHSO-UHFFFAOYSA-N