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Product Description
MDK-7933 is a potent HDAC8 inhibitor with an IC₅₀ of 27.2 nM in cancer cell lines. MDK-7933 displays antiproliferative effects toward several human lung cancer cell lines (A549, H1299, and CL1-5).
MDK-7933 is a potent HDAC8 inhibitor with an IC₅₀ of 27.2 nM in cancer cell lines. MDK-7933 displays antiproliferative effects toward several human lung cancer cell lines (A549, H1299, and CL1-5).
Biovision | B2119 | MDK-7933 DataSheet
Alternate Name/Synonyms: (E)-N-hydroxy-3-(5-methoxy-[1,1':4',1''-terphenyl]-2-yl)acrylamide; HDAC8-IN-1
Appearance: Crystalline solid
Formulation: N/A
CAS Number: 1417997-93-3
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₂H₁₉NO₃
Molecular Weight: 345.4
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A potent HDAC8 inhibitor
MDL Number: N/A
PubChem CID: N/A
SMILES: ONC(/C=C/C1=CC=C(C=C1C2=CC=C(C=C2)C3=CC=CC=C3)OC)=O
InChi: nChI=1S/C22H19NO3/c1-26-20-13-11-19(12-14-22(24)23-25)21(15-20)18-9-7-17(8-10-18)16-5-3-2-4-6-16/h2-15,25H,1H3,(H,23,24)/b14-12+
InChi Key: ASHPRZYGCOMVHO-WYMLVPIESA-N
