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Product Description
A potent, irreversible, and specific inhibitor of the peroxidation activity of myeloperoxidase (MPO; IC₅₀ = 300 nM). Does not affect catalase or glutathione peroxidase activities. Also displays no effect on the production of superoxide by neutrophils. Shown to inhibit H₂O₂-induced apoptosis in HL-60, human leukemia cells.
Myeloperoxidase Inhibitor is a potent, irreversible, and specific inhibitor of the peroxidation activity of myeloperoxidase (MPO; IC₅₀ = 300 nM). Does not affect catalase or glutathione peroxidase activities. Also displays no effect on the production of superoxide by neutrophils. Shown to inhibit H₂O₂-induced apoptosis in HL-60, human leukemia cells.
Biovision | 1977 | Myeloperoxidase Inhibitor DataSheet
Alternate Name/Synonyms: 4-Aminobenzoic hydrazide; MPO Inhibitor; 4-ABH
Appearance: White to off-white solid
Formulation: N/A
CAS Number: 5351-17-7
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₇H9N₃O
Molecular Weight: 151.17
Cell-Permeable?: Yes
Purity: ≥95% by HPLC
Solubilities: DMSO
Handling: Protect from light and mositure
Country of Origin: USA
Tag Line: A potent myeloperoxidase (MPO) inhibitor
MDL Number: MFCD00007606
PubChem CID: 21450
SMILES: C1=CC(=CC=C1C(=O)NN)N
InChi: InChI=1S/C7H9N3O/c8-6-3-1-5(2-4-6)7(11)10-9/h1-4H,8-9H2,(H,10,11)
InChi Key: WPBZMCGPFHZRHJ-UHFFFAOYSA-N
