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Product Description
Nimustine is a nitrosourea compound that displays anticancer activity. Nimustine induces DNA cross-linking and double-stranded DNA breaks. Nimustine is clinically used to treat gliomas and may also downregulate expression of DNA ligase IV.
Nimustine is a nitrosourea compound that displays anticancer activity. Nimustine induces DNA cross-linking and double-stranded DNA breaks. Nimustine is clinically used to treat gliomas and may also downregulate expression of DNA ligase IV.
Biovision | B2069 | Nimustine hydrochloride DataSheet
Alternate Name/Synonyms: 3-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-1-(2-chloroethyl)-1-nitrosourea hydrochloride; NSC-245,382; NSC245,382
Appearance: White to yellow solid
Formulation: N/A
CAS Number: 55661-38-6
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₉H₁₄Cl₂N₆O₂
Molecular Weight: 309.15
Cell-Permeable?: Yes
Purity: ≥97%
Solubilities: DMSO (>20 mg/ml) or H₂O (>30 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: An anticancer agent
MDL Number: MFCD01676942
PubChem CID: 91657
SMILES: CC1=NC=C(C(=N1)N)CNC(=O)N(CCCl)N=O.Cl
InChi: InChI=1S/C9H13ClN6O2.ClH/c1-6-12-4-7(8(11)14-6)5-13-9(17)16(15-18)3-2-10;/h4H,2-3,5H2,1H3,(H,13,17)(H2,11,12,14);1H
InChi Key: KPMKNHGAPDCYLP-UHFFFAOYSA-N
