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Product Description
Optovin is a reversible photoactive TRPA1 activator. It specifically activates TRPA1 (EC₅₀ = 2 μM) but not TRPV1 or TRPM8. Optovin activates human TRPA1 via structure-dependent photochemical reactions with redox-sensitive cysteine residues, and enables control of motor activity in paralyzed extremities by localized illumination in animals.
Optovin is a reversible photoactive TRPA1 activator. It specifically activates TRPA1 (EC₅₀ = 2 μM) but not TRPV1 or TRPM8. Optovin activates human TRPA1 via structure-dependent photochemical reactions with redox-sensitive cysteine residues, and enables control of motor activity in paralyzed extremities by localized illumination in animals.
Biovision | 9594 | Optovin DataSheet
Alternate Name/Synonyms: 5-[[2,5-Dimethyl-1-(3-pyridinyl)-1H-pyrrol-3-yl]methylene]-2-thioxo-4-thiazolidinone
Appearance: Orange solid
Formulation: N/A
CAS Number: 348575-88-2
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₅H₁₃N₃OS₂
Molecular Weight: 315.41
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (>30 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A reversible photoactive TRPA1 activator
MDL Number: N/A
PubChem CID: 1365101
SMILES: CC1=CC(=C(N1C2=CN=CC=C2)C)C=C3C(=O)NC(=S)S3
InChi: InChI=1S/C15H13N3OS2/c1-9-6-11(7-13-14(19)17-15(20)21-13)10(2)18(9)12-4-3-5-16-8-12/h3-8H,1-2H3,(H,17,19,20)/b13-7+
InChi Key: YISGMOZSGOGYOU-NTUHNPAUSA-N
